4-bromo-3,5-difluorotoluene
$200.00
CAS No.: 1805120-10-8
Catalog No.: 194044
Purity: 95%
MF: C7H5BrF2
MW: 207.017
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C)C=C1F)F
Catalog No.: 194044
Purity: 95%
MF: C7H5BrF2
MW: 207.017
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C)C=C1F)F
4-bromo-3,5-difluorotoluene; CAS No.: 1805120-10-8; 4-bromo-3,5-difluorotoluene. PROPERTIES: 4-bromo-3,5-difluorotoluene is a colorless to pale yellow liquid with a molecular weight of 214.0 g/mol. It has a boiling point around 145-147 C at 760 mmHg and exhibits low water solubility while being miscible with common organic solvents such as dichloromethane, ethyl acetate, and tetrahydrofuran. The compound contains a bromine substituent and fluorine atoms, which impart significant chemical stability and distinct reactivity patterns. Proper storage requires keeping the compound in a tightly sealed container at temperatures below 20 C, protected from light and moisture. Safety precautions include using protective gloves, eye protection, and ensuring adequate ventilation during handling. The compound may cause serious eye damage and skin irritation, and appropriate first aid measures should be followed in case of exposure. APPLICATIONS: 4-bromo-3,5-difluorotoluene serves as a versatile intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and specialty chemicals. Its unique substitution pattern makes it suitable for cross-coupling reactions, enabling the synthesis of complex aromatic systems for medicinal applications. In the field of medicinal chemistry, it functions as a building block for certain antiviral agents and antibiotics, as documented in recent pharmaceutical research publications. The bromine substituent provides a convenient handle for further functionalization, such as in Suzuki-Miyaura couplings. Additionally, the compound is utilized in the production of liquid crystalline materials, where the fluorinated architecture contributes to desired physical properties. In materials science, it serves as a precursor to certain types of conductive polymers and sensors. The strategic positioning of the bromine and fluorine substituents allows for selective derivatization, expanding its utility in organic synthesis, as described in recent advances in fluorine chemistry.
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