3-phenyl-1H-pyrazol-4-amine
$250.00
CAS No.: 91857-86-2
Catalog No.: 192882
Purity: 95%
MF: C9H9N3
MW: 159.192
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NNC=C1N
Catalog No.: 192882
Purity: 95%
MF: C9H9N3
MW: 159.192
Storage: 2-8 degree Celsius
SMILES: C1(=CC=CC=C1)C1=NNC=C1N
3-phenyl-1H-pyrazol-4-amine; CAS No.: 91857-86-2; 3-phenyl-1H-pyrazol-4-amine. PROPERTIES: This compound presents as a white crystalline solid with molecular formula C9H9N3 and a molecular weight of 159.19 g/mol. It exhibits a melting point in the range of 148-152 C and demonstrates moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to oxidation and should be stored under inert atmosphere. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as 3-phenyl-1H-pyrazol-4-amine may cause skin irritation. The amine group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, 3-phenyl-1H-pyrazol-4-amine serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its phenyl substituent enables improved lipophilicity for enhanced membrane permeability. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The pyrazole ring system also facilitates coordination with metal ions, making it valuable for creating coordination polymers in materials science applications, as evidenced by structural chemistry publications.
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