3-bromo-5-iodophenol
$250.00
CAS No.: 570391-20-7
Catalog No.: 197058
Purity: 95%
MF: C6H4BrIO
MW: 298.905
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C=C(C1)I)O
Catalog No.: 197058
Purity: 95%
MF: C6H4BrIO
MW: 298.905
Storage: 2-8 degree Celsius
SMILES: BrC=1C=C(C=C(C1)I)O
3-bromo-5-iodophenol; CAS No.: 570391-20-7; 3-bromo-5-iodophenol. PROPERTIES: This bromo-iodo-substituted phenol features molecular formula C?H?BrIO with molecular weight 295.96 g/mol. It generally appears as a white crystalline powder. Soluble in polar aprotic solvents like DMF and DMSO. Melting point approximately 100-105 C. Exhibits IR absorption for hydroxyl groups (~3300 cm??) and C-Br/C-I groups (~600-500 cm??). Thermogravimetric analysis reveals weight loss onset above 150 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a bromo-iodo-substituted phenol, 3-bromo-5-iodophenol is predominantly utilized in the synthesis of biaryl-containing pharmaceuticals. It serves as a key intermediate in constructing biaryl scaffolds through Suzuki-Miyaura coupling reactions, where the bromo and iodo substituents provide valuable sites for cross-coupling as demonstrated in medicinal chemistry research (Journal of Medicinal Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its phenol group forms covalent bonds with target biomolecules (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyaryl ethers with enhanced flame retardancy, where the bromo and iodo substituents contribute to improved fire-resistant characteristics (Polymer International).
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