2-bromo-5-chlorophenylacetonitrile
$200.00
CAS No.: 127792-49-8
Catalog No.: 197059
Purity: 95%
MF: C8H5BrClN
MW: 230.492
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C=C1)Cl)CC#N
Catalog No.: 197059
Purity: 95%
MF: C8H5BrClN
MW: 230.492
Storage: 2-8 degree Celsius
SMILES: BrC1=C(C=C(C=C1)Cl)CC#N
2-bromo-5-chlorophenylacetonitrile; CAS No.: 127792-49-8; 2-bromo-5-chlorophenylacetonitrile. PROPERTIES: This bromo-chloro-substituted phenylacetonitrile features molecular formula C?H?BrClN with molecular weight 230.54 g/mol. It typically exists as a colorless liquid. Soluble in non-polar and slightly polar organic solvents like hexanes and ethyl acetate. Boiling point approximately 150-155 C. Exhibits IR absorption for nitrile (~2220 cm??) and C-Br/C-Cl groups (~600-500 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a bromo-chloro-substituted phenylacetonitrile, 2-bromo-5-chlorophenylacetonitrile is predominantly utilized in the synthesis of agrochemicals. It serves as a key intermediate in constructing phenylpyrazoline herbicides, where the bromo and chloro groups provide valuable binding affinity for plant enzymes as demonstrated in pesticide chemistry research (Pest Management Science). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its nitrile functionality enables conjugation to biomolecules via click chemistry reactions (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyurethane foams with enhanced thermal stability, where the bromo and chloro substituents contribute to improved flame retardancy and mechanical properties (Polymer International).
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