The store will not work correctly when cookies are disabled.
We use cookies for optimal website function and to better serve our customers. By continuing to browse you agree to the storing of cookies on your device. See our privacy policy for details.
Allow cookies Deny
3-bromo-2,6-difluoroaniline; CAS No.: 1262198-07-1;3-bromo-2,6-difluoroaniline. PROPERTIES: 3-bromo-2,6-difluoroaniline is a brominated and fluorinated aromatic amine with molecular formula C6H5BrF2N. It typically exists as a colorless to pale yellow liquid with a boiling point around 140-145 C. The compound has limited water solubility but dissolves well in organic solvents like chloroform or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic bromine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic molecules. The bromo and difluoro substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions, while the amine group offers additional functionality for further elaboration (The Journal of Organic Chemistry). In pharmaceutical development, 3-bromo-2,6-difluoroaniline contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).