3,5-dichloro-4-(trifluoromethyl)aniline
$200.00
CAS No.: 496052-55-2
Catalog No.: 193959
Purity: 95%
MF: C7H4Cl2F3N
MW: 230.016
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(N)C=C(C1C(F)(F)F)Cl
Catalog No.: 193959
Purity: 95%
MF: C7H4Cl2F3N
MW: 230.016
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(N)C=C(C1C(F)(F)F)Cl
3,5-dichloro-4-(trifluoromethyl)aniline; CAS No.: 496052-55-2;3,5-dichloro-4-(trifluoromethyl)aniline. PROPERTIES: 3,5-dichloro-4-(trifluoromethyl)aniline is a chlorinated and trifluoromethylated aromatic amine with molecular formula C7H5Cl2F3N. It typically exists as a colorless to pale yellow liquid with a boiling point around 140-145 C. The compound has limited water solubility but dissolves well in organic solvents like dichloromethane or THF. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic chlorine-containing fumes. Proper storage involves keeping it in tightly sealed containers below 20 C, protected from light and moisture. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic systems. The dichloro and trifluoromethyl substituents provide multiple sites for cross-coupling and nucleophilic substitution reactions, while the amine group offers additional functionality for further elaboration (The Journal of Organic Chemistry). In pharmaceutical development, 3,5-dichloro-4-(trifluoromethyl)aniline contributes to the synthesis of antimicrobial agents where the halogenated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-deficient aromatic core modulates the electronic properties of derived materials (Advanced Materials).
Reviews
Write Your Own Review