2-fluoro-3-hydroxybenzonitrile
$200.00
CAS No.: 1000339-24-1
Catalog No.: 193930
Purity: 95%
MF: C7H4FNO
MW: 137.113
Storage: 2-8 degree Celsius
SMILES: FC1=C(C#N)C=CC=C1O
Catalog No.: 193930
Purity: 95%
MF: C7H4FNO
MW: 137.113
Storage: 2-8 degree Celsius
SMILES: FC1=C(C#N)C=CC=C1O
2-fluoro-3-hydroxybenzonitrile; CAS No.: 1000339-24-1;2-fluoro-3-hydroxybenzonitrile. PROPERTIES: 2-fluoro-3-hydroxybenzonitrile is a fluorinated and hydroxylated aromatic nitrile with molecular formula C7H4FNO2. It typically exists as a white to off-white crystalline powder with a melting point of approximately 120-125 C. The compound has limited water solubility but dissolves in basic aqueous solutions. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong acids, releasing toxic nitrogen-containing fumes. Proper storage involves keeping it in tightly sealed containers below 25 C, protected from moisture and heat. APPLICATIONS: In pharmaceutical research, this compound serves as a lead structure for developing antimicrobial and anticancer agents. The fluoro and hydroxy substitution provides structural diversity that enhances binding to biological targets, while the nitrile group forms the pharmacophore essential for activity (European Journal of Medicinal Chemistry). In materials science, 2-fluoro-3-hydroxybenzonitrile contributes to the creation of functional organic materials with tailored electronic properties. Its fluorinated aromatic core and nitrile group influence the electronic characteristics of derived materials, useful in optoelectronic applications such as organic field-effect transistors (Journal of Materials Chemistry C). The hydroxyl group enables further functionalization through esterification or etherification, expanding its utility in multistep syntheses (The Journal of Organic Chemistry).
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