(2-amino-3-chloro-5-fluorophenyl)methanol
$225.00
CAS No.: 2089319-92-4
Catalog No.: 193128
Purity: 95%
MF: C7H7ClFNO
MW: 175.59
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=C(C=C1Cl)F)CO
Catalog No.: 193128
Purity: 95%
MF: C7H7ClFNO
MW: 175.59
Storage: 2-8 degree Celsius
SMILES: NC1=C(C=C(C=C1Cl)F)CO
(2-amino-3-chloro-5-fluorophenyl)methanol; CAS No.: 2089319-92-4 (2-amino-3-chloro-5-fluorophenyl)methanol. PROPERTIES: (2-amino-3-chloro-5-fluorophenyl)methanol is a crystalline powder with a molecular weight of 183.6 g/mol. It has a melting point between 105-110 C and exhibits low water solubility. The compound is moderately soluble in DMSO and DMF. When handling (2-amino-3-chloro-5-fluorophenyl)methanol, care should be taken to avoid inhalation of dust and skin contact. Protective equipment including a lab coat, gloves, and a respirator is recommended. The compound should be stored in a tightly sealed container at 2-8 C, preferably under an inert atmosphere to prevent oxidation. It is sensitive to acidic conditions, which may cause degradation. APPLICATIONS: (2-amino-3-chloro-5-fluorophenyl)methanol serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of antiviral and anticancer agents. Its amino and hydroxyl groups provide multiple sites for chemical modification, as demonstrated in the synthesis of kinase inhibitors reported in Bioorganic & Medicinal Chemistry Letters. The chloro and fluoro substituents allow for fine-tuning of the compound's pharmacokinetic properties. In materials science, derivatives of this compound have been investigated for their potential in organic electronics, as described in Advanced Functional Materials. Additionally, (2-amino-3-chloro-5-fluorophenyl)methanol can be utilized in the preparation of fluorescent probes for bioimaging applications, as highlighted in Chemical Communications.
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