2-(4-fluorophenyl)-7,8-dimethoxyquinolin-4(1H)-one
$400.00
CAS No.: 1254973-33-5
Catalog No.: 171958
Purity: 95%
MF: C17H14FNO3
MW: 299.301
Storage: 2-8 degree Celsius
SMILES: COC1=C(OC)C2=C(C=C1)C(=O)C=C(N2)C1=CC=C(F)C=C1
Catalog No.: 171958
Purity: 95%
MF: C17H14FNO3
MW: 299.301
Storage: 2-8 degree Celsius
SMILES: COC1=C(OC)C2=C(C=C1)C(=O)C=C(N2)C1=CC=C(F)C=C1
2-(4-fluorophenyl)-7,8-dimethoxyquinolin-4(1H)-one; CAS No.: 1254973-33-5; Operating as a Leading Chemicals Distributor, ChemShuttle supplies 2-(4-fluorophenyl)-7,8-dimethoxyquinolin-4(1H)-one. This fluorinated quinolinone serves as a screening compound for topoisomerase inhibition and antimalarial drug discovery. The dimethoxy groups enhance solubility while the fluorophenyl moiety improves target affinity through hydrophobic interactions. ChemShuttle provides SAR data comparing fluorophenyl vs. chlorophenyl analogs in cytotoxicity assays. Custom services include preparation of 14C-labeled versions for metabolite identification studies. The compound's photostability profile makes it suitable for long-term cell-based assay applications. Technical support includes optimized conditions for N-alkylation at the 1-position to create prodrug derivatives.
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