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2-(4-fluorophenyl)-7,8-dimethoxyquinolin-4(1H)-one

2-(4-fluorophenyl)-7,8-dimethoxyquinolin-4(1H)-one

4-(4-methoxyquinolin-2-yl)benzene-1,2-diol

4-(4-methoxyquinolin-2-yl)benzene-1,2-diol

2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxyquinolin-4(1H)-one

$400.00
CAS No.: 1313738-75-8
Catalog No.: 171994
Purity: 95%
MF: C18H17NO5
MW: 327.336
Storage: 2-8 degree Celsius
SMILES: COC1=CC2=C(C=C1)C(=O)C(O)=C(N2)C1=CC(OC)=C(OC)C=C1
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171994
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2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxyquinolin-4(1H)-one; CAS No.: 1313738-75-8; ChemShuttle's expertise in CRO chemical synthesis is demonstrated through 2-(3,4-dimethoxyphenyl)-3-hydroxy-7-methoxyquinolin-4(1H)-one. This multi-methoxylated quinolinone acts as a key intermediate for antimalarial drug discovery. The methoxy groups provide electron-donating effects that stabilize radical intermediates in heme polymerization inhibition. Applications include Plasmodium falciparum growth inhibition studies. The company provides IC50 data against drug-resistant malaria strains. Custom services include preparation of 14C-labeled versions for metabolite profiling in hepatic microsome models.

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