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2,3-dimethyl-4-bromofluorobenzene; CAS No.: 52548-00-2;2,3-dimethyl-4-bromofluorobenzene. PROPERTIES: 2,3-dimethyl-4-bromofluorobenzene is a brominated and fluorinated aromatic compound with molecular formula C8H8BrFO. It typically exists as a colorless liquid with a boiling point around 150-155 C. The compound has limited water solubility but dissolves well in organic solvents like ether or toluene. It exhibits moderate thermal stability but may decompose when exposed to high temperatures or strong bases, releasing toxic bromine vapors. Proper storage involves keeping it in tightly sealed containers below 20 C, away from heat sources and incompatible materials. APPLICATIONS: In organic synthesis, this compound serves as a versatile intermediate for creating complex aromatic systems. The bromo substituent enables cross-coupling reactions to form biaryl structures, while the fluoro group provides additional sites for functionalization (Tetrahedron Letters). In pharmaceutical development, 2,3-dimethyl-4-bromofluorobenzene contributes to the synthesis of antimicrobial agents where the brominated aromatic scaffold enhances binding to microbial targets (Antimicrobial Agents and Chemotherapy). The compound also finds application in materials science as a building block for organic electronics, where its electron-withdrawing bromo and fluoro groups modulate the electronic properties of derived materials (Journal of Materials Chemistry C).