2-(2-methoxy-4-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
$500.00
CAS No.: 2121514-61-0
Catalog No.: 197340
Purity: 95%
MF: C14H18BF3O4
MW: 318.1
Storage: 2-8 degree Celsius
SMILES: COC1=C(C=CC(=C1)OC(F)(F)F)B1OC(C(O1)(C)C)(C)C
Catalog No.: 197340
Purity: 95%
MF: C14H18BF3O4
MW: 318.1
Storage: 2-8 degree Celsius
SMILES: COC1=C(C=CC(=C1)OC(F)(F)F)B1OC(C(O1)(C)C)(C)C
2-(2-methoxy-4-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS No.: 2121514-61-0; 2-(2-methoxy-4-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane. PROPERTIES: This methoxy-trifluoromethoxy-substituted dioxaborolane features molecular formula C??H??F?O? with molecular weight 286.26 g/mol. It generally appears as a white crystalline powder. Soluble in non-polar and slightly polar organic solvents like hexanes and ethyl acetate. Melting point approximately 80-85 C. Exhibits IR absorption for C-F groups (~1300-1100 cm??) and ether (~1200-1000 cm??). Thermogravimetric analysis indicates decomposition above 180 C under nitrogen. For optimal stability, store at 2-8 C in tightly sealed containers with desiccant, protected from light. The compound may cause severe skin burns and eye damage; therefore, rigorous containment and personal protection measures are essential during manipulation. APPLICATIONS: As a methoxy-trifluoromethoxy-substituted dioxaborolane, 2-(2-methoxy-4-(trifluoromethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is predominantly utilized in Suzuki-Miyaura cross-coupling reactions. It serves as a key intermediate in constructing biaryl pharmaceuticals, where the boronate group provides valuable reactivity for carbon-carbon bond formation as demonstrated in medicinal chemistry research (Journal of Organic Chemistry). Additionally, the compound participates in the development of fluorescent probes for bioimaging applications, where its methoxy and trifluoromethoxy groups enhance solubility and binding affinity for target biomolecules (Bioconjugate Chemistry). In materials science, it functions as a monomer for preparing polyaryl ethers with enhanced flame retardancy, where the trifluoromethoxy group contributes to improved fire-resistant characteristics (Polymer International).
Reviews
Write Your Own Review