[2,2'-binaphthalene]-6,6'-dicarboxylic acid
$300.00
CAS No.: 932033-58-4
Catalog No.: LT0203
Purity: 95%
MF: C22H14O4
MW: 342.35
Storage: 2-8 degree Celsius
SMILES: C1=C(C=CC2=CC(=CC=C12)C(=O)O)C1=CC2=CC=C(C=C2C=C1)C(=O)O
Catalog No.: LT0203
Purity: 95%
MF: C22H14O4
MW: 342.35
Storage: 2-8 degree Celsius
SMILES: C1=C(C=CC2=CC(=CC=C12)C(=O)O)C1=CC2=CC=C(C=C2C=C1)C(=O)O
CAS NO.: 932033-58-4;[2,2'-binaphthalene]-6,6'-dicarboxylic acid. PROPERTIES: This binaphthalene dicarboxylic acid presents as a white crystalline solid with a molecular weight of approximately 426.4 g/mol. The [2,2'-binaphthalene]-6,6'-dicarboxylic acid combines a binaphthalene framework with two carboxylic acid groups. It exhibits limited aqueous solubility until pH < 3 but dissolves well in DMSO and DMF. Stability characterization reveals vulnerability to acid-catalyzed decarboxylation and base-promoted racemization, necessitating storage at 2-8 degree Celsius in sealed glass containers. Handlers should use powder hoods with HEPA filtration and wear cut-resistant gloves during handling. Skin contact may cause localized edema requiring corticosteroid application. Inhalation may induce respiratory alkalosis; treatment includes humidified oxygen administration. Eye exposure requires chelation inhibitors and ophthalmology evaluation. Waste should be hydrolyzed with dilute acid prior to disposal. APPLICATIONS: The [2,2'-binaphthalene]-6,6'-dicarboxylic acid serves as a key intermediate in the synthesis of various pharmaceuticals and agrochemicals (excluding agricultural applications). Its binaphthalene framework provides opportunities for constructing complex aromatic systems through Suzuki-Miyaura cross-coupling reactions. Research teams utilize this compound as a starting material for creating fluorescent probes and bioimaging agents. The dicarboxylic acid groups undergo esterification or amide bond formation for further functionalization. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity and chiral catalysts for asymmetric synthesis.
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