1-methyl-1,2,3,4-tetrahydroquinolin-4-one; CAS No.: 1198-15-8; 1-methyl-1,2,3,4-tetrahydroquinolin-4-one. PROPERTIES: 1-methyl-1,2,3,4-tetrahydroquinolin-4-one is a crystalline compound with molecular formula C9H10N2O. It has a melting point between 110-115 C and exhibits moderate solubility in ethanol and methanol. The compound should be stored in a tightly sealed container at room temperature away from strong oxidizing agents. Safety precautions include avoiding contact with eyes and skin due to its potential to cause serious eye damage and skin irritation. APPLICATIONS: This methyl-substituted tetrahydroquinolinone is employed in the development of alkaloid mimetics. The tetrahydroquinoline structure provides unique binding affinity as described in natural products chemistry journals. In chemical biology, 1-methyl-1,2,3,4-tetrahydroquinolin-4-one serves as a building block for creating fluorescent biosensors. According to bioanalytical chemistry journals, the tetrahydroquinoline scaffold's natural fluorescence allows for detection of specific analytes with limits approaching picomolar concentrations.