1-(4-chlorophenyl)-N-methylmethanamine
$400.00
CAS No.: 104-11-0
Catalog No.: 196510
Purity: 95%
MF: C8H10ClN
MW: 155.628
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)CNC
Catalog No.: 196510
Purity: 95%
MF: C8H10ClN
MW: 155.628
Storage: 2-8 degree Celsius
SMILES: ClC1=CC=C(C=C1)CNC
1-(4-chlorophenyl)-N-methylmethanamine; CAS No.: 104-11-0; 1-(4-chlorophenyl)-N-methylmethanamine. PROPERTIES: 1-(4-chlorophenyl)-N-methylmethanamine is a colorless liquid with a characteristic amine odor. It has a molecular formula of C9H11ClN, a molecular weight of 166.64 g/mol, and a boiling point of approximately 172-174 C. The compound is moderately soluble in water and miscible with common organic solvents. It is hygroscopic and should be stored under inert atmosphere (nitrogen or argon) at temperatures below 10 C to prevent decomposition. Safety precautions include using explosion-proof equipment and avoiding open flames. It is classified as a flammable liquid (Flash Point: 63 C) and a category 2 eye irritant. APPLICATIONS: 1-(4-chlorophenyl)-N-methylmethanamine is extensively used in the pharmaceutical industry as a key intermediate in the synthesis of antipsychotic drugs, particularly phenothiazine derivatives. Its chlorophenyl group provides essential lipophilicity for blood-brain barrier penetration. In the field of materials science, this compound serves as a building block for the preparation of conductive polymers with improved electrochemical properties. It is also employed in the synthesis of chiral ligands for asymmetric catalysis, particularly in palladium-catalyzed cross-coupling reactions, as described in Organic Letters. Additionally, the compound functions as a precursor for the preparation of liquid crystalline materials used in display technologies, where its rigid aromatic core and flexible amine group contribute to favorable mesomorphic properties.
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