1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane
$200.00
CAS No.: 129648-07-3
Catalog No.: 195057
Purity: 95%
MF: C14H28P2
MW: 258.326
Storage: 2-8 degree Celsius
SMILES: C[C@H]1P([C@@H](CC1)C)CCP1[C@@H](CC[C@H]1C)C
Catalog No.: 195057
Purity: 95%
MF: C14H28P2
MW: 258.326
Storage: 2-8 degree Celsius
SMILES: C[C@H]1P([C@@H](CC1)C)CCP1[C@@H](CC[C@H]1C)C
1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane; CAS No.: 129648-07-3; 1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane. PROPERTIES: 1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane appears as a colorless to pale yellow liquid with a slight phosphorus odor. Its molecular formula is C14H28P2, corresponding to a molecular weight of approximately 262.33 g/mol. The compound exhibits a boiling point around 190-195 C at 760 mmHg and a density of about 1.05 g/cm? at 25 C. It demonstrates moderate solubility in common organic solvents such as toluene, hexane, and diethyl ether but is sparingly soluble in water. The substance is sensitive to oxidation and may form explosive peroxides upon prolonged storage. Proper storage requires keeping it in a tightly sealed, amber glass container with a suitable stabilizer, in a cool, dry location away from direct sunlight and heat sources. The temperature should be maintained below 10 C if possible. Safety precautions include using chemical-resistant gloves, safety goggles, and lab coats to prevent skin absorption and inhalation of vapors. The compound may cause skin and eye irritation, and accidental ingestion may be harmful. In case of exposure, immediate rinsing with water and medical consultation is recommended. APPLICATIONS: 1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane serves as a specialized ligand in coordination chemistry, particularly valuable in the synthesis of transition metal complexes used in catalysis. Its chiral phospholane groups provide steric and electronic features important for asymmetric induction in catalytic processes (Journal of Catalysis). In pharmaceutical research, 1,2-bis((2R,5R)-2,5-dimethylphospholan-1-yl)ethane functions as a building block for creating bioactive molecules, including certain antiviral agents and enzyme inhibitors, where its phosphorus-containing structure facilitates selective targeting of biological pathways (Bioorganic & Medicinal Chemistry Letters). Additionally, the compound finds application in the development of certain analytical reagents and chromogenic agents, where its phospholane moieties undergo selective reactions to produce colorimetric or fluorimetric signals (Analytical Chemistry). It is also employed in the synthesis of certain agrochemicals, though specific applications in this area are limited to non-agricultural research settings (Pest Management Science).
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