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tert-butyl 7-bromo-2-aza-bicyclo[2.2.1]heptane-2-carboxylate; CAS No.: 1221818-32-1; Operating as a Chemical Online Store, ChemShuttle supplies tert-butyl 7-bromo-2-aza-bicyclo[2.2.1]heptane-2-carboxylate. This brominated azabicyclic compound acts as a key intermediate for cross-coupling reactions in fragment expansion strategies. The bromine atom at the bridgehead position enables Buchwald-Hartwig aminations or Suzuki-Miyaura couplings to introduce aromatic pharmacophores. The bicyclic framework provides enhanced three-dimensionality for addressing flatland challenges in lead optimization. ChemShuttle's online platform facilitates rapid procurement with real-time inventory tracking, supporting medicinal chemists in creating sp3-rich compounds for allosteric modulator development. Technical datasheets include detailed Stille coupling reaction conditions optimized for this substrate.