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tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate
$400.00
CAS No.: 2089301-60-8
Catalog No.: 193219
Purity: 95%
MF: C17H21N3O5
MW: 347.371
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C=1C=C2C(=CC1)NC(C21CCN(CC1)C(=O)OC(C)(C)C)=O
Catalog No.: 193219
Purity: 95%
MF: C17H21N3O5
MW: 347.371
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C=1C=C2C(=CC1)NC(C21CCN(CC1)C(=O)OC(C)(C)C)=O
tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate; CAS No.: 2089301-60-8; tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate. PROPERTIES: This compound is a tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate appearing as white crystalline powder. Its molecular weight is approximately 451.48 g/mol. It has melting point around 140-145 C. The compound is moderately soluble in common organic solvents like dimethylformamide. It's moisture sensitive and may hydrolyze upon exposure to atmospheric moisture. Store in tightly sealed containers under nitrogen atmosphere. Keep below 25 C and protect from moisture. Handle with care using appropriate protective equipment when handling powder. APPLICATIONS: tert-Butyl 5-nitro-2-oxospiro[indoline-3,4'-piperidine]-1'-carboxylate is used in organic synthesis as nitrospirocyclic building block as detailed in Journal of Organic Chemistry. It's employed in preparation of certain kinase inhibitors mentioned in Journal of Medicinal Chemistry. Additionally, this compound serves as intermediate for synthesizing spirocyclic pharmaceuticals reported in Bioconjugate Chemistry. The nitro group provides valuable electron-withdrawing effect beneficial in receptor binding applications.
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