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tert-butyl 4-hydroxy-3-(trifluoromethyl)piperidine-1-carboxylate; CAS No.: 1283720-71-7; ChemShuttle's expertise in Small molecules synthesis is showcased through tert-butyl 4-hydroxy-3-(trifluoromethyl)piperidine-1-carboxylate. This trifluoromethylated piperidine serves as a key intermediate for CF3-containing drug candidates. The hydroxyl group enables glycosylation or phosphorylation for prodrug strategies, while the CF3 group enhances target binding through hydrophobic interactions. Applications include HIV protease inhibitors and TRPV1 antagonists. The company provides computational modeling data predicting binding poses in common pharmacological targets. Scale-up services maintain strict control over diastereomeric ratios through chiral chromatography.