tert-butyl 3-methyl-4-nitrophenylcarbamate
$225.00
CAS No.: 1380445-45-3
Catalog No.: 193090
Purity: 95%
MF: C12H16N2O4
MW: 252.27
Storage: 2-8 degree Celsius
SMILES: CC=1C=C(C=CC1[N+](=O)[O-])NC(OC(C)(C)C)=O
Catalog No.: 193090
Purity: 95%
MF: C12H16N2O4
MW: 252.27
Storage: 2-8 degree Celsius
SMILES: CC=1C=C(C=CC1[N+](=O)[O-])NC(OC(C)(C)C)=O
tert-butyl 3-methyl-4-nitrophenylcarbamate; CAS No.: 1380445-45-3; tert-butyl 3-methyl-4-nitrophenylcarbamate. PROPERTIES: This compound appears as a white crystalline powder with molecular formula C11H16N2O4 and a molecular weight of 236.26 g/mol. It demonstrates a melting point in the range of 128-132 C and shows moderate solubility in common organic solvents like methanol and ethyl acetate. The substance is sensitive to hydrolysis and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at temperatures below 25 C, protected from moisture and light. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as tert-butyl 3-methyl-4-nitrophenylcarbamate may cause skin irritation. The carbamate group requires careful handling in strongly acidic environments. APPLICATIONS: In the pharmaceutical industry, tert-butyl 3-methyl-4-nitrophenylcarbamate serves as an intermediate for synthesizing non-steroidal anti-inflammatory drugs (NSAIDs), as described in medicinal chemistry literature focusing on carbamate derivatives. Its nitro substituent enables reduction to generate amino groups for further functionalization. Additionally, this compound functions as a building block for preparing agrochemicals with fungicidal activities through coupling reactions. Academic research has explored its potential in metal coordination chemistry for creating luminescent sensors, as reported in inorganic chemistry journals. The phenylcarbamate structure also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.
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