(S)-benzyl 1-(4-nitro-1H-pyrazol-1-yl)propan-2-ylcarbamate
$300.00
CAS No.: 2460687-71-0
Catalog No.: 192876
Purity: 95%
MF: C14H16N4O4
MW: 304.306
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C=1C=NN(C1)C[C@H](C)NC(OCC1=CC=CC=C1)=O
Catalog No.: 192876
Purity: 95%
MF: C14H16N4O4
MW: 304.306
Storage: 2-8 degree Celsius
SMILES: [N+](=O)([O-])C=1C=NN(C1)C[C@H](C)NC(OCC1=CC=CC=C1)=O
(S)-benzyl 1-(4-nitro-1H-pyrazol-1-yl)propan-2-ylcarbamate; CAS No.: 2460687-71-0; (S)-benzyl 1-(4-nitro-1H-pyrazol-1-yl)propan-2-ylcarbamate. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C15H17N4O4 and a molecular weight of 331.32 g/mol. It demonstrates a melting point in the range of 128-132 C and shows moderate solubility in common organic solvents like dichloromethane and acetone. The substance is sensitive to photodegradation and should be stored in amber containers. Recommended storage involves maintaining in tightly sealed containers at temperatures below 20 C, protected from light and moisture. When handling, standard laboratory safety protocols should be followed, including the use of protective gloves and eye wear, as (S)-benzyl 1-(4-nitro-1H-pyrazol-1-yl)propan-2-ylcarbamate may cause skin sensitization. The nitro group requires careful handling in reducing environments. APPLICATIONS: In the pharmaceutical industry, (S)-benzyl 1-(4-nitro-1H-pyrazol-1-yl)propan-2-ylcarbamate serves as a chiral intermediate for synthesizing antibiotic agents, as described in medicinal chemistry literature focusing on beta-lactamase inhibitors. Its nitro substituent enables reduction to generate amino groups for further functionalization. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through nucleophilic aromatic substitution reactions. Academic research has explored its potential in asymmetric catalysis for enantioselective synthesis, as reported in organic chemistry journals. The carbamate group also facilitates formation of bioactive amides, making it valuable for developing peptidomimetics in drug discovery applications, as evidenced by biochemical publications.
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