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(S)-2-amino-3-(benzyloxy)propan-1-ol hydrochloride; CAS No.: 61366-43-6; (S)-2-amino-3-(benzyloxy)propan-1-ol hydrochloride. PROPERTIES: This compound appears as a white to off-white crystalline solid with molecular formula C10H14N2O2 {HCl and a molecular weight of 216.69 g/mol. It exhibits a melting point in the range of 138-142 C and demonstrates good solubility in water and common polar solvents like methanol. The substance is hygroscopic and should be stored in dry conditions. Recommended storage involves maintaining in tightly sealed containers at room temperature with protection from moisture and light. When handling, standard laboratory safety precautions should be observed, including the use of gloves and eye protection, as (S)-2-amino-3-(benzyloxy)propan-1-ol hydrochloride may cause skin and eye irritation. The amino group requires careful handling in strongly acidic environments. APPLICATIONS: In medicinal chemistry, (S)-2-amino-3-(benzyloxy)propan-1-ol hydrochloride serves as a key intermediate for synthesizing antidepressant agents, as documented in pharmaceutical research focusing on serotonergic compounds. Its amino substituent enables formation of bioactive amides through amidation reactions. Additionally, this compound functions as a building block for preparing agrochemicals with insecticidal activities through formation of urea derivatives. Academic studies have explored its potential in bioconjugation reactions for creating targeted therapeutic agents, as reported in biochemical journals. The propanol framework also facilitates formation of metal-organic frameworks (MOFs), making it valuable for gas storage applications in materials science, as evidenced by studies in crystallography publications.