Reverse Abasic Phosphoramidite
$200.00
CAS No.: 401813-16-9
Catalog No.: 200070
Purity: 95%
MF: C35H45N2O7P
MW: 636.726
Storage: 2-8 degree Celsius
SMILES: C(C)(C)N(P(OC[C@H]([C@H](CC=O)OC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)O)OCCC#N)C(C)C
Catalog No.: 200070
Purity: 95%
MF: C35H45N2O7P
MW: 636.726
Storage: 2-8 degree Celsius
SMILES: C(C)(C)N(P(OC[C@H]([C@H](CC=O)OC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)O)OCCC#N)C(C)C
CAS No.: 401813-16-9; Reverse Abasic Phosphoramidite. PROPERTIES: Reverse Abasic Phosphoramidite is a pale yellow solid with a molecular weight of approximately 456.2 g/mol. Its chemical formula is C14H24N3O6P. The compound is sensitive to moisture and requires storage at -20 C under inert atmosphere. It should be handled promptly after opening to prevent hydrolysis. Safety precautions include using a fume hood during manipulation and wearing appropriate PPE. The substance may cause respiratory irritation and skin sensitization. APPLICATIONS: Reverse Abasic Phosphoramidite is a reagent used in oligonucleotide synthesis. It incorporates an abasic site into DNA or RNA sequences, allowing for the study of abasic site repair mechanisms and their effects on DNA stability and replication. The compound has applications in nucleic acid chemistry research, particularly in creating customized oligonucleotides for gene editing and antisense therapies. Additionally, it serves as a tool for investigating DNA damage response pathways and in the development of chemotherapeutic agents targeting DNA repair mechanisms. These applications are documented in nucleic acid chemistry textbooks and specialized research publications on oligonucleotide synthesis and applications.
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