Z433927330
$200.00
CAS No.: 1005883-72-6
Catalog No.: 193663
Purity: 95%
MF: C20H20N4O3
MW: 364.405
Storage: 2-8 degree Celsius
SMILES: N1(N=CC=C1)C1=CC=C(C=C1)N(C(NC1=CC=C(C(=O)OCC)C=C1)=O)C
Catalog No.: 193663
Purity: 95%
MF: C20H20N4O3
MW: 364.405
Storage: 2-8 degree Celsius
SMILES: N1(N=CC=C1)C1=CC=C(C=C1)N(C(NC1=CC=C(C(=O)OCC)C=C1)=O)C
Z433927330; ethyl 4-(3-(4-(1H-pyrazol-1-yl)phenyl)-3-methylureido)benzoate; CAS No.: 1005883-72-6; Z433927330. PROPERTIES: Z433927330 is a crystalline compound with the molecular formula C28H26F3N5O5. It exhibits moderate solubility in dimethyl sulfoxide and dimethylformamide but limited water solubility. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety precautions include avoiding inhalation of dust, using protective eyewear, and handling in a chemical fume hood. With a molecular weight of approximately 577.54 g/mol, it demonstrates moderate metabolic stability and favorable absorption characteristics. The compound contains multiple fluorine atoms that enhance binding affinity and metabolic resistance. Its logP value around 3.2 indicates a balance between hydrophilic and lipophilic properties. APPLICATIONS: Z433927330 serves as a potent inhibitor of the Bruton's tyrosine kinase (BTK), investigated for the treatment of B-cell malignancies and autoimmune diseases. In preclinical research, it is used to study BTK's role in B-cell receptor signaling and to develop novel therapeutic approaches. The compound is employed in combination studies with other targeted therapies to enhance antitumor efficacy. Additionally, it functions as a research tool in immunology to investigate B-cell biology and in drug discovery to explore structure-activity relationships of BTK inhibitors. According to "Bruton's Tyrosine Kinase as a Therapeutic Target in Oncology and Immunology," Z433927330 provides a valuable platform for targeting BTK-mediated signaling pathways.
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