H-Asp(Oet)-OEt.HCl
$300.00
CAS No.: 16115-68-7
Catalog No.: WLZ1382
Purity: 95%
MF: C8H16ClNO4
MW: 225.672
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H](CC(=O)OCC)C(=O)OCC
Catalog No.: WLZ1382
Purity: 95%
MF: C8H16ClNO4
MW: 225.672
Storage: 2-8 degree Celsius
SMILES: Cl.N[C@@H](CC(=O)OCC)C(=O)OCC
CAS No.: 16115-68-7; H-Asp(Oet)-OEt.HCl. PROPERTIES: H-Asp(Oet)-OEt.HCl is an aspartic acid derivative with molecular formula C8H13NO5.HCl and molar mass 223.7 g/mol. It exists as white hygroscopic powder with deliquescent tendencies. The compound is freely soluble in water (up to 500 mg/mL) and ethanol. Recommended storage is in desiccated containers at room temperature. Safety considerations include using closed-system transfers to prevent hygroscopic caking and wearing respiratory protection during powder handling. APPLICATIONS: In peptide synthesis, H-Asp(Oet)-OEt.HCl serves as an aspartic acid building block with temporary protection of the carboxylic acid group. Its application in creating acid-labile protecting group strategies is detailed in Tetrahedron Letters synthetic methodology papers. For prodrug development, the diethyl ester functionality enables hydrolytic activation in physiological conditions, as reported in Journal of Medicinal Chemistry pharmacokinetic studies. In chemical biology, the compound is used in creating activity-based probes for aspartic proteases, with Chemistry & Biology publications describing covalent inhibitor design applications. Additionally, researchers employ this reagent in studying peptide coupling reactions, with Synthesis journal articles outlining optimization of coupling conditions for improved peptide synthesis yields.
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