Rosuvastatin methyl ester
$200.00
CAS No.: 147118-40-9
Catalog No.: 109945
Purity: 95%
MF: C23H30FN3O6S
MW: 495.573
Storage: 2-8 degree Celsius
SMILES: COC(=O)C[C@H](O)C[C@H](O)\C=C\C1=C(N=C(N=C1C1=CC=C(F)C=C1)N(C)S(C)(=O)=O)C(C)C
Catalog No.: 109945
Purity: 95%
MF: C23H30FN3O6S
MW: 495.573
Storage: 2-8 degree Celsius
SMILES: COC(=O)C[C@H](O)C[C@H](O)\C=C\C1=C(N=C(N=C1C1=CC=C(F)C=C1)N(C)S(C)(=O)=O)C(C)C
Rosuvastatin methyl ester; (3R,5S,E)-methyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate; CAS No.: 147118-40-9; ChemShuttle provides building blocks for drug discovery like this dihydroxyheptenoate statin precursor. The (3R,5S,E) configuration and fluorophenyl-pyrimidine group are optimized for HMG-CoA reductase binding. Our synthesis employs asymmetric dihydroxylation and Stille couplings for stereocontrolled assembly. The methyl ester prodrug form enhances oral bioavailability in preclinical testing.
Reviews
Write Your Own Review