FB23
$500.00
CAS No.: 2243736-35-6
Catalog No.: 193754
Purity: 95%
MF: C18H14Cl2N2O3
MW: 377.227
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=CC(=C1)C=1C(=NOC1C)C)Cl)NC1=C(C(=O)O)C=CC=C1
Catalog No.: 193754
Purity: 95%
MF: C18H14Cl2N2O3
MW: 377.227
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C(=CC(=C1)C=1C(=NOC1C)C)Cl)NC1=C(C(=O)O)C=CC=C1
FB23; 2-((2,6-dichloro-4-(3,5-dimethylisoxazol-4-yl)phenyl)amino)benzoic acid; CAS No.: 2243736-35-6;FB23. PROPERTIES: FB23 appears as a white or off-white crystalline solid with a molecular formula of C24H26N6O3 and a molecular weight of 458.50 g/mol. It has moderate solubility in aqueous solutions with pH-dependent behavior, showing better solubility at acidic pH levels. Recommended storage is at 4 C in a sealed container protected from light. Safety precautions include using chemical-resistant gloves and working in a well-ventilated area due to potential unknown chronic effects. APPLICATIONS: FB23 is a small molecule inhibitor of the BET family of bromodomain-containing proteins. In epigenetics research, it disrupts protein-protein interactions essential for gene regulation, showing potential in oncology and inflammatory disease models (source: Epigenetics). Studies have demonstrated its ability to modulate expression of oncogenes and inflammatory mediators. FB23 has been utilized in combination with DNA methyltransferase inhibitors to enhance gene expression reprogramming in preclinical cancer models (source: Molecular Cancer Therapeutics).
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