2-(5-(5-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid

2-(5-(5-(4-(2-bromo-5-fluorophenoxy)piperidin-1-yl)-1,3,4-thiadiazol-2-yl)-2H-tetrazol-2-yl)acetic acid

A939572

$400.00
CAS No.: 1032229-33-6
Catalog No.: 193755
Purity: 95%
MF: C20H22ClN3O3
MW: 387.867
Storage: 2-8 degree Celsius
SMILES: ClC1=C(OC2CCN(CC2)C(=O)NC2=CC(=CC=C2)C(NC)=O)C=CC=C1
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193755
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A939572; 4-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)phenyl)piperidine-1-carboxamide; CAS No.: 1032229-33-6;A939572. PROPERTIES: A939572 is a white to pale yellow powder with a molecular formula of C23H20ClN5O2 and a molecular weight of 433.89 g/mol. It has limited water solubility but dissolves in dimethyl sulfoxide and dimethylformamide. Proper storage requires keeping it at -20 C in a sealed amber vial to prevent photodegradation. When handling, protective eyewear and gloves are recommended due to its pharmaceutical nature and potential for causing skin irritation. APPLICATIONS: A939572 is a potent and selective inhibitor of the aryl hydrocarbon receptor (AhR), involved in xenobiotic metabolism and immune regulation. In toxicology research, it helps study AhR-mediated cellular responses and dioxin toxicity mechanisms (source: Toxicological Sciences). The compound has been used to investigate AhR's role in immune cell differentiation, particularly in regulatory T cell development. Additionally, A939572 serves as a tool for exploring therapeutic strategies in autoimmune diseases where AhR modulation shows promise (source: Journal of Immunology).

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