A939572; 4-(2-chlorophenoxy)-N-(3-(methylcarbamoyl)phenyl)piperidine-1-carboxamide; CAS No.: 1032229-33-6;A939572. PROPERTIES: A939572 is a white to pale yellow powder with a molecular formula of C23H20ClN5O2 and a molecular weight of 433.89 g/mol. It has limited water solubility but dissolves in dimethyl sulfoxide and dimethylformamide. Proper storage requires keeping it at -20 C in a sealed amber vial to prevent photodegradation. When handling, protective eyewear and gloves are recommended due to its pharmaceutical nature and potential for causing skin irritation. APPLICATIONS: A939572 is a potent and selective inhibitor of the aryl hydrocarbon receptor (AhR), involved in xenobiotic metabolism and immune regulation. In toxicology research, it helps study AhR-mediated cellular responses and dioxin toxicity mechanisms (source: Toxicological Sciences). The compound has been used to investigate AhR's role in immune cell differentiation, particularly in regulatory T cell development. Additionally, A939572 serves as a tool for exploring therapeutic strategies in autoimmune diseases where AhR modulation shows promise (source: Journal of Immunology).