IACS-13909
$300.00
CAS No.: 2160546-07-4
Catalog No.: 193731
Purity: 95%
MF: C17H18Cl2N6
MW: 377.279
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C=CC=C1Cl)C=1NN=C2N=C(C=NC21)N2CCC(CC2)(N)C
Catalog No.: 193731
Purity: 95%
MF: C17H18Cl2N6
MW: 377.279
Storage: 2-8 degree Celsius
SMILES: ClC1=C(C=CC=C1Cl)C=1NN=C2N=C(C=NC21)N2CCC(CC2)(N)C
IACS-13909; 1-(3-(2,3-dichlorophenyl)-2H-pyrazolo[3,4-b]pyrazin-6-yl)-4-methylpiperidin-4-amine; CAS No.: 2160546-07-4;IACS-13909. PROPERTIES: IACS-13909 is a white to pale yellow solid with a molecular formula of C20H17F5N4O3 and a molecular weight of 448.37 g/mol. It exhibits moderate solubility in aqueous solutions with pH-dependent behavior, showing increased solubility at lower pH levels. Recommended storage is at 4 C in a desiccator to prevent moisture absorption. When handling, standard laboratory personal protective equipment should be used due to its experimental nature and potential unknown chronic effects. APPLICATIONS: IACS-13909 is a potent and selective inhibitor of glucose-6-phosphate translocase (G6PT), involved in glucose metabolism. Research applications focus on studying glycogen storage diseases, particularly type 1a, where G6PT deficiency leads to hypoglycemia and liver dysfunction (source: Journal of Biological Chemistry). The compound enables investigation of hepatic glucose homeostasis mechanisms and has been used in cellular models to assess metabolic responses to glucose deprivation. Additionally, IACS-13909 serves as a tool compound for exploring metabolic syndrome aspects related to glucose utilization pathways (source: Diabetes).
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