IMT1
$200.00
CAS No.: 2304621-31-4
Catalog No.: 193680
Purity: 95%
MF: C21H21NO4
MW: 351.402
Storage: 2-8 degree Celsius
SMILES: CN(C(C(C)OC1=CC=C2C(=CC(OC2=C1)=O)C1=C(C=CC=C1)C)=O)C
Catalog No.: 193680
Purity: 95%
MF: C21H21NO4
MW: 351.402
Storage: 2-8 degree Celsius
SMILES: CN(C(C(C)OC1=CC=C2C(=CC(OC2=C1)=O)C1=C(C=CC=C1)C)=O)C
IMT1; N,N-dimethyl-2-((2-oxo-4-(o-tolyl)-2H-chromen-7-yl)oxy)propanamide; CAS No.: 2304621-31-4; IMT1. PROPERTIES: IMT1 is a white crystalline powder with the molecular formula C23H20F3N5O3. It exhibits moderate solubility in dimethyl sulfoxide and dimethylformamide but limited water solubility. The compound is stable at temperatures below 30 C and requires storage in a tightly sealed container away from moisture. Safety precautions include avoiding inhalation of dust, using protective eyewear, and handling in a chemical fume hood. With a molecular weight of approximately 471.43 g/mol, it demonstrates moderate metabolic stability and favorable pharmacokinetic properties. The compound has multiple fluorine atoms that enhance binding affinity and metabolic resistance. Its logP value around 2.5 indicates a balance between solubility and membrane permeability. APPLICATIONS: IMT1 functions as a selective inhibitor of the mechanistic target of rapamycin complex 1 (mTORC1), investigated for anticancer therapy and the treatment of other mTOR-driven diseases. In preclinical research, it is used to study mTOR signaling pathways and to develop novel therapeutic strategies. The compound is employed in combination studies with other targeted therapies to enhance antitumor efficacy. Additionally, it serves as a research tool in cell biology to investigate mTOR-mediated cellular processes and in drug discovery to explore structure-activity relationships of mTOR inhibitors. According to "mTOR Inhibitors: A Comprehensive Review," IMT1 represents a promising candidate for modulating mTOR signaling in various disease contexts.
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