CAS No.: 3614-69-5; Dimethindene maleate. PROPERTIES: Dimethindene maleate is a white or almost white crystalline powder with a molecular weight of 394.4 g/mol. Its chemical formula is C22H26N2O4. The compound is practically insoluble in water but freely soluble in methanol and ethanol. It should be stored in a cool, dry place below 30 C in airtight containers protected from light. Safety measures include avoiding inhalation of dust and using PPE during handling. The substance is harmful if swallowed and may cause skin irritation. APPLICATIONS: Dimethindene maleate is an antihistaminic agent belonging to the alkylamine group. It acts as a selective H1 receptor antagonist used primarily in the treatment of allergic conditions such as urticaria, allergic rhinitis, and pruritus. Clinical studies indicate its efficacy in reducing histamine-induced skin reactions. The compound has also found applications in veterinary medicine for treating allergic manifestations in animals. Additionally, Dimethindene maleate is utilized in cosmetic formulations as a soothing agent for skin irritations. These applications are documented in pharmaceutical references including the Martindale: The Complete Drug Reference.