MK2 Inhibitor III
$300.00
CAS No.: 724711-21-1
Catalog No.: 193724
Purity: 95%
MF: C21H16N4O
MW: 340.386
Storage: 2-8 degree Celsius
SMILES: N1=CC(=CC2=CC=CC=C12)C1=NC=CC(=C1)C1=CC=2C(NCCC2N1)=O
Catalog No.: 193724
Purity: 95%
MF: C21H16N4O
MW: 340.386
Storage: 2-8 degree Celsius
SMILES: N1=CC(=CC2=CC=CC=C12)C1=NC=CC(=C1)C1=CC=2C(NCCC2N1)=O
MK2 Inhibitor III; 2-(2-(quinolin-3-yl)pyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one; CAS No.: 724711-21-1; MK2 Inhibitor III. PROPERTIES: MK2 Inhibitor III is a white to off-white powder with the molecular formula C23H25N5O3S. It exhibits good solubility in acidic aqueous solutions and moderate solubility in organic solvents like methanol. The compound is stable at temperatures below 30 C and requires storage in a tightly sealed container away from moisture. Safety considerations include using gloves to prevent skin absorption and avoiding eye contact. With a molecular weight of approximately 471.54 g/mol, it demonstrates moderate metabolic stability and favorable pharmacokinetic properties. The compound has sulfur-containing groups and hydrogen bond donors/acceptors that enhance target binding. Its logP value around 2.5 indicates a balance between hydrophilic and lipophilic characteristics. APPLICATIONS: MK2 Inhibitor III serves as a selective inhibitor of the mitogen-activated protein kinase-activated protein kinase 2 (MK2), investigated for the treatment of inflammatory diseases and cancer. In preclinical research, it is used to study MK2's role in inflammation and stress responses and to develop novel therapeutic strategies. The compound is employed in combination studies with other anti-inflammatory agents to enhance treatment efficacy. Additionally, it functions as a research tool in cell signaling to investigate MK2-mediated pathways and in drug discovery to explore novel approaches to targeting MK2 in disease contexts. According to "MK2 Inhibitors: From Discovery to Therapeutic Applications," MK2 Inhibitor III provides a promising approach to modulating inflammation and stress signaling.
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