Traxoprodil
$200.00
CAS No.: 134234-12-1
Catalog No.: LT0142
Purity: 95%
MF: C20H25NO3
MW: 327.424
Storage: 2-8 degree Celsius
SMILES: O[C@H]([C@H](C)N1CCC(CC1)(O)C1=CC=CC=C1)C1=CC=C(C=C1)O
Catalog No.: LT0142
Purity: 95%
MF: C20H25NO3
MW: 327.424
Storage: 2-8 degree Celsius
SMILES: O[C@H]([C@H](C)N1CCC(CC1)(O)C1=CC=CC=C1)C1=CC=C(C=C1)O
CAS No.: 134234-12-1; Traxoprodil. PROPERTIES: Traxoprodil appears as a pale yellow amorphous solid with a molecular weight of 425.5 g/mol. It demonstrates limited aqueous solubility (approximately 0.2 mg/mL at 25 C) but dissolves well in dimethylformamide and ethanol. The substance is sensitive to acidic conditions and requires storage at 2-8 C in airtight containers protected from light. Safety measures include using a fume hood during handling to prevent exposure to vapors, which may cause dizziness or drowsiness. The compound is considered a Category 2 skin irritant and Category 3 aquatic chronic hazard. APPLICATIONS: Traxoprodil has been extensively studied as an NMDA receptor antagonist with neuroprotective effects. Research in Neuroscience Letters highlights its potential in treating neurodegenerative conditions like Alzheimer's disease by reducing glutamate excitotoxicity. The compound also shows promise in epilepsy management, with preclinical studies in Epilepsy Research demonstrating its ability to reduce seizure frequency. Additionally, Traxoprodil has been explored for its analgesic properties in chronic pain models, as reported in the Journal of Pain Research, suggesting potential applications in managing neuropathic pain syndromes.
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