ZD7288
$365.00
CAS No.: 133059-99-1
Catalog No.: 194896
Purity: 95%
MF: C15H21ClN4
MW: 292.814
Storage: 2-8 degree Celsius
SMILES: [Cl-].C(C)C1=NC(=[N+](C(=C1NC1=CC=CC=C1)NC)C)C
Catalog No.: 194896
Purity: 95%
MF: C15H21ClN4
MW: 292.814
Storage: 2-8 degree Celsius
SMILES: [Cl-].C(C)C1=NC(=[N+](C(=C1NC1=CC=CC=C1)NC)C)C
ZD7288; 4-ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride; CAS No.: 133059-99-1;ZD7288. PROPERTIES: ZD7288 is a white to off-white crystalline solid with a molecular formula of C19H21N3O and a molecular weight of 315.39 g/mol. It has limited aqueous solubility but dissolves in dimethyl sulfoxide. Proper storage requires maintaining it at -20 C in a sealed container protected from light. When handling, chemical-resistant gloves and eye protection are recommended due to potential skin and eye irritation. APPLICATIONS: ZD7288 is a potent and selective inhibitor of the If (funny) current in cardiac cells. In cardiovascular research, it serves as a tool for studying sinoatrial node physiology and cardiac rhythm regulation (source: Journal of Pharmacology and Experimental Therapeutics). Preclinical studies have evaluated its efficacy in models of sick sinus syndrome and bradyarrhythmias. Additionally, ZD7288 provides insights into the molecular mechanisms of cardiac pacemaker activity and aids in developing novel therapeutic approaches for cardiac arrhythmias (source: Cardiovascular Research).
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