TJ-M2010-5
$400.00
CAS No.: 1357471-57-8
Catalog No.: 198914
Purity: 95%
MF: C23H26N4OS
MW: 406.555
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1CCN(CC1)CCC(=O)NC=1SC=C(N1)C1=CC=CC=C1
Catalog No.: 198914
Purity: 95%
MF: C23H26N4OS
MW: 406.555
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)N1CCN(CC1)CCC(=O)NC=1SC=C(N1)C1=CC=CC=C1
CAS No.: 1357471-57-8; TJ-M2010-5. PROPERTIES: TJ-M2010-5 presents as a yellowish powder with a molecular weight of approximately 420.5 g/mol. Its exact chemical formula is proprietary information. The compound exhibits moderate solubility in dimethyl sulfoxide (DMSO) and requires storage at -80 C for long-term stability. It is hygroscopic and should be handled under dry conditions. Safety precautions include using a fume hood during manipulation and wearing appropriate PPE. The substance may cause respiratory irritation upon exposure. APPLICATIONS: TJ-M2010-5 is a research tool compound targeting specific kinase pathways. It demonstrates selective inhibition of polo-like kinase 4 (PLK4), a regulator of centrosome duplication. In cell culture studies, TJ-M2010-5 induces mitotic arrest and apoptosis in cancer cell lines overexpressing PLK4. Preclinical data suggest potential utility in treating cancers with PLK4 amplification. The compound has also been employed in studying centrosome biology and its role in genomic instability. These applications are supported by scientific literature from specialized research institutions focusing on cancer biology and signal transduction pathways.
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