Quiflapon
$200.00
CAS No.: 136668-42-3
Catalog No.: 193678
Purity: 95%
MF: C34H35ClN2O3S
MW: 587.185
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)SC1=C(N(C2=CC=C(C=C12)OCC1=NC2=CC=CC=C2C=C1)CC1=CC=C(C=C1)Cl)CC(C(=O)O)(C)C
Catalog No.: 193678
Purity: 95%
MF: C34H35ClN2O3S
MW: 587.185
Storage: 2-8 degree Celsius
SMILES: C(C)(C)(C)SC1=C(N(C2=CC=C(C=C12)OCC1=NC2=CC=CC=C2C=C1)CC1=CC=C(C=C1)Cl)CC(C(=O)O)(C)C
Quiflapon; 3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl)-2,2-dimethylpropanoic acid; CAS No.: 136668-42-3; Quiflapon. PROPERTIES: Quiflapon is a crystalline compound with the molecular formula C16H12Cl2N2O2. It exhibits moderate solubility in water and polar organic solvents. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a sealed container. Safety precautions include using chemical-resistant gloves, avoiding skin contact, and ensuring proper disposal of contaminated materials. With a molecular weight of approximately 341.20 g/mol, it demonstrates moderate absorption and distribution characteristics. The compound contains chlorinated aromatic rings contributing to its binding affinity and chemical stability. Its logP value around 2.6 indicates a balance between hydrophilic and lipophilic properties. APPLICATIONS: Quiflapon serves as a calcium channel blocker, investigated for the treatment of cardiovascular conditions such as hypertension and angina. In pharmacological research, it is used to study calcium channel regulation in vascular smooth muscle cells and to develop novel antihypertensive agents. The compound is employed in preclinical models to evaluate blood pressure-lowering effects and in combination studies with other antihypertensives to enhance therapeutic efficacy. Additionally, it functions as a research tool in cardiovascular biology to investigate ion channel physiology and in drug discovery to explore novel approaches to calcium channel modulation. According to "Calcium Channel Blockers in Cardiovascular Therapy," Quiflapon provides insights into the therapeutic potential of targeting calcium channels in hypertension management.
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