Luzindole
$300.00
CAS No.: 117946-91-5
Catalog No.: 193669
Purity: 95%
MF: C19H20N2O
MW: 292.382
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)C=1NC2=CC=CC=C2C1CCNC(C)=O
Catalog No.: 193669
Purity: 95%
MF: C19H20N2O
MW: 292.382
Storage: 2-8 degree Celsius
SMILES: C(C1=CC=CC=C1)C=1NC2=CC=CC=C2C1CCNC(C)=O
Luzindole; N-(2-(2-benzyl-1H-indol-3-yl)ethyl)acetamide; CAS No.: 117946-91-5; Luzindole. PROPERTIES: Luzindole is a white crystalline compound with the molecular formula C17H12N2O. It exhibits low solubility in water but dissolves moderately in organic solvents like methanol and dimethyl sulfoxide. The compound is stable at room temperature but recommended storage involves protection from light and moisture in a desiccator. Safety considerations include using chemical-resistant gloves, avoiding skin contact, and ensuring proper disposal of contaminated materials. With a molecular weight of approximately 252.29 g/mol, it demonstrates moderate absorption and distribution characteristics. The compound has a planar aromatic structure that contributes to its binding affinity for certain receptor targets. Its logP value around 2.8 indicates a balance between hydrophilic and lipophilic properties. APPLICATIONS: Luzindole serves as a selective antagonist of the melatonin receptor, investigated in chronobiology research and the study of circadian rhythms. In pharmacological research, it is used to study the role of melatonin receptors in sleep regulation and to develop novel chronotherapeutic agents. The compound is employed in preclinical models to evaluate effects on sleep-wake cycles and in combination studies with other hypnotics to enhance therapeutic efficacy. Additionally, it functions as a research tool in neuropharmacology to investigate receptor subtype selectivity and in drug design to explore structure-activity relationships of melatonin receptor ligands. According to "Melatonin Receptor Ligands: From Basic Research to Clinical Applications," Luzindole provides valuable insights into the therapeutic potential of targeting melatonin receptors.
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