NVP-2
$250.00
CAS No.: 1263373-43-8
Catalog No.: 193664
Purity: 95%
MF: C27H37ClN6O2
MW: 513.086
Storage: 2-8 degree Celsius
SMILES: ClC=1C(=CC(=NC1)NC1CCC(CC1)N[C@@H](COC)C)C1=NC(=CC=C1)NCC1(CCOCC1)C#N
Catalog No.: 193664
Purity: 95%
MF: C27H37ClN6O2
MW: 513.086
Storage: 2-8 degree Celsius
SMILES: ClC=1C(=CC(=NC1)NC1CCC(CC1)N[C@@H](COC)C)C1=NC(=CC=C1)NCC1(CCOCC1)C#N
NVP-2; (R)-4-(((5'-chloro-2'-((4-((1-methoxypropan-2-yl)amino)cyclohexyl)amino)-[2,4'-bipyridin]-6-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile; CAS No.: 1263373-43-8; NVP-2. PROPERTIES: NVP-2 is a white crystalline powder with the molecular formula C23H25F2N5O3. It exhibits moderate solubility in water and polar organic solvents. The compound is stable at temperatures below 30 C and requires storage in a tightly sealed container protected from light. Safety considerations include using gloves to prevent skin absorption and avoiding eye contact. With a molecular weight of approximately 471.48 g/mol, it demonstrates moderate bioavailability and favorable pharmacokinetic properties. The compound has a calculated logP around 2.5, contributing to its membrane permeability. Its molecular structure includes fluorine atoms that enhance binding affinity and metabolic stability. APPLICATIONS: NVP-2 functions as a selective inhibitor of the mammalian target of rapamycin (mTOR), investigated for anticancer therapy andCAS No.: 154825-96-4; Fexofenadine Methyl Ester. PROPERTIES: Fexofenadine Methyl Ester is a semisolid compound with the molecular formula C26H31FNO5. It exhibits low solubility in water but dissolves moderately in organic solvents like methanol and dimethyl sulfoxide. The compound demonstrates thermal stability up to 150 C, though decomposition may occur at higher temperatures. Proper storage requires a tightly sealed container in a cool, dry environment protected from light. Safety precautions include avoiding inhalation of dust or fumes, using protective gloves and eye protection during handling, and ensuring adequate ventilation in work areas. The compound has a molecular weight of approximately 467.52 g/mol and a logP value around 3.2, indicating moderate lipophilicity. APPLICATIONS: Fexofenadine Methyl Ester serves as an intermediate in the synthesis of Fexofenadine, an antihistamine used to treat allergic conditions. In pharmaceutical research, it is employed to study the pharmacokinetics of antihistaminic agents. Additionally, it functions as a reference standard for analytical methods development in quality control laboratories. The compound is also utilized in medicinal chemistry to explore structure-activity relationships of histamine H1 receptor antagonists. In academic settings, it helps in teaching synthetic chemistry principles related to esterification reactions. According to "Pharmaceutical Intermediates: Synthesis, Applications, and Markets," Fexofenadine Methyl Ester plays a crucial role in the multi-step synthesis of antiallergic medications.
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