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AMG-900; N-(4-((3-(2-aminopyrimidin-4-yl)pyridin-2-yl)oxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine; CAS No.: 945595-80-2; N-(4-((3-(2-Aminopyrimidin-4-yl)pyridin-2-yl)oxy)phenyl)-4-(4-methylthiophen-2-yl)phthalazin-1-amine, a multicyclic amine, exemplifies our pharma building blocks for FLT3 inhibitors in leukemia research. The aminopyrimidine and thiophene motifs enhance kinase binding. Our custom synthesis employs CADD-guided design to optimize ADMET properties.