MPP+ iodide
$500.00
CAS No.: 36913-39-0
Catalog No.: 193784
Purity: 95%
MF: C12H12IN
MW: 297.139
Storage: 2-8 degree Celsius
SMILES: [I-].C[N+]1=CC=C(C=C1)C1=CC=CC=C1
Catalog No.: 193784
Purity: 95%
MF: C12H12IN
MW: 297.139
Storage: 2-8 degree Celsius
SMILES: [I-].C[N+]1=CC=C(C=C1)C1=CC=CC=C1
MPP+ iodide; 1-methyl-4-phenylpyridin-1-ium iodide; CAS No.: 36913-39-0;MPP+ iodide. PROPERTIES: MPP+ iodide is a white or off-white crystalline powder with a molecular formula of C11H14N5 I and a molecular weight of 357.26 g/mol. It has good water solubility and is stable under standard laboratory conditions. Storage should be at room temperature in a tightly sealed container. Safety considerations include avoiding skin contact and inhalation, with standard laboratory protective measures recommended due to its neurotoxic potential. APPLICATIONS: MPP+ iodide is a well-known neurotoxin used in Parkinson's disease research. It selectively damages dopaminergic neurons in the substantia nigra pars compacta after being taken up by dopamine transporters (source: Journal of Neurochemistry). In vitro and in vivo models utilize MPP+ to induce parkinsonian phenotypes, enabling study of disease mechanisms and potential therapeutic interventions. It also serves as a tool for investigating mitochondrial dysfunction and oxidative stress in neurodegenerative processes (source: Neurobiology of Disease).
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