Ald-Ph-amido-PEG3-NHS ester

Ald-Ph-amido-PEG3-NHS ester

MC-Gly-Gly-Phe-Gly

MC-Gly-Gly-Phe-Gly

N3-PEG3-CH2CH2-Boc

$350.00
CAS No.: 252881-73-5
Catalog No.: 199186
Purity: 95%
MF: C13H25N3O5
MW: 303.359
Storage: 2-8 degree Celsius
SMILES: N(=[N+]=[N-])CCOCCOCCOCCC(=O)OC(C)(C)C
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CAS No.: 252881-73-5; N3-PEG3-CH2CH2-Boc. PROPERTIES: N3-PEG3-CH2CH2-Boc is a colorless viscous liquid with a molecular weight of approximately 377.3 g/mol. Its chemical formula is C12H23N3O4. The compound is soluble in common organic solvents such as dimethylformamide and dioxane. It requires storage at 2-8 C to maintain stability. The substance is sensitive to acid and should be handled under inert atmosphere. Safety considerations include avoiding skin contact and using gloves during manipulation. The compound may cause skin irritation and serious eye damage. APPLICATIONS: N3-PEG3-CH2CH2-Boc is a versatile building block in bioconjugation chemistry. It combines an azide group for click chemistry reactions with a tert-butoxycarbonyl (Boc) protecting group. The PEG spacer provides solubility modulation and steric hindrance control. Applications include the synthesis of PEGylated biomolecules, creation of bioorthogonal probes, and development of targeted drug delivery systems. The compound has been employed in creating antibody-drug conjugates with improved pharmacokinetic properties. Additionally, it serves as a key intermediate in nanoparticle functionalization for biomedical applications. These applications are documented in bioconjugation chemistry textbooks and specialized research publications on drug delivery systems.

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