CAS NO.: 171228-49-2; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one (Posaconazole; SCH 56592). PROPERTIES: Posaconazole is a white to off-white powder. It has low solubility in water and is soluble in organic solvents such as ethanol and propylene glycol. It should be stored at room temperature in a tightly closed container, protected from light and moisture. As an antifungal drug, it should be handled with care to avoid accidental ingestion or contact with skin and eyes. APPLICATIONS: Posaconazole is widely used in clinical medicine for the treatment and prevention of fungal infections. It works by inhibiting the synthesis of ergosterol, an essential component of the fungal cell membrane. It is effective against a broad spectrum of fungi, including Candida, Aspergillus, and some zygomycetes. Its application in antifungal therapy is supported by clinical guidelines and numerous clinical trials in the field of infectious diseases and pharmacology.