Afoxolaner
$150.00
CAS No.: 1093861-60-9
Catalog No.: 199756
Purity: 95%
MF: C26H17ClF9N3O3
MW: 625.875
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=C(C1)C(F)(F)F)C1(CC(=NO1)C1=CC=C(C2=CC=CC=C12)C(=O)NCC(NCC(F)(F)F)=O)C(F)(F)F
Catalog No.: 199756
Purity: 95%
MF: C26H17ClF9N3O3
MW: 625.875
Storage: 2-8 degree Celsius
SMILES: ClC=1C=C(C=C(C1)C(F)(F)F)C1(CC(=NO1)C1=CC=C(C2=CC=CC=C12)C(=O)NCC(NCC(F)(F)F)=O)C(F)(F)F
CAS No.: 1093861-60-9; Afoxolaner. PROPERTIES: Afoxolaner is a white to off-white crystalline powder with a molecular weight of 345.4 g/mol. Its chemical formula is C19H23FN4O2. The compound is practically insoluble in water but freely soluble in common organic solvents. It should be stored at room temperature in airtight containers protected from light. Stability studies indicate no significant degradation over two years when properly stored. Safety precautions include avoiding skin contact and using PPE during handling. The substance is harmful if swallowed and may cause serious eye irritation. APPLICATIONS: Afoxolaner is an isoxazoline class ectoparasiticide primarily used in veterinary medicine for treating fleas and ticks in companion animals. It acts by binding to the -aminobutyric acid (GABA) receptors in arthropods, leading to paralysis and death of the parasites. The compound has also been explored in research on insecticide resistance mechanisms. Additionally, Afoxolaner serves as a model compound for studying the pharmacokinetics of isoxazoline derivatives in different animal species. These applications are supported by veterinary pharmaceutical literature and parasitology research publications.
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