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Angiotensin II; (2S,5S,8S,11S,14S,17S)-2-((1H-imidazol-4-yl)methyl)-17-amino-5-((S)-sec-butyl)-1-((S)-2-(((S)-1-carboxy-2-phenylethyl)carbamoyl)pyrrolidin-1-yl)-14-(3-guanidinopropyl)-8-(4-hydroxybenzyl)-11-isopropyl-1,4,7,10,13,16-hexaoxo-3,6,9,12,15-pentaazanonadecan-19-oic acid; CAS No.: 4474-91-3; Angiotensin II. PROPERTIES: Angiotensin II is an octapeptide hormone appearing as a white or tan lyophilized powder. This Angiotensin II has a molecular weight of 1046.18 g/mol. It is hygroscopic and should be stored at -20 C in a tightly sealed container. The compound is sensitive to light and should be protected from prolonged exposure. In terms of safety, Angiotensin II may cause respiratory irritation and skin/eye irritation upon exposure. APPLICATIONS: Angiotensin II serves as a key molecule in cardiovascular research, used to study blood pressure regulation and renal function. It is employed in pharmacology to investigate the renin-angiotensin system and the effects of angiotensin-converting enzyme inhibitors. In cell biology, Angiotensin II is used to study smooth muscle contraction and vascular biology. In clinical settings, it is used as a vasoconstrictor in the treatment of certain cases of shock. These applications are documented in cardiovascular research journals and pharmacology literature.