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ARRY-380; 6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine; CAS No.: 937265-83-3; 6-[5-[[[2-(Methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4-quinazolinamine, a multifunctional quinazoline, highlights our key intermediates for multi-kinase inhibition. The methylsulfonyl group modulates ATP-binding affinity. ChemShuttle s CRO chemical synthesis employs reductive amination for efficient linker attachment.