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3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride
$800.00
CAS No.: 1629249-40-6
Catalog No.: TQP0949
Purity: 95%
MF: C29H38ClN5O2
MW: 524.109
Storage: 2-8 degree Celsius
SMILES: Cl.CC1=NN(C(=C1)C)C=1C=C(C=CC1)C(CC(=O)O)CN1CC(CC1)CCC1=NC=2NCCCC2C=C1
Catalog No.: TQP0949
Purity: 95%
MF: C29H38ClN5O2
MW: 524.109
Storage: 2-8 degree Celsius
SMILES: Cl.CC1=NN(C(=C1)C)C=1C=C(C=CC1)C(CC(=O)O)CN1CC(CC1)CCC1=NC=2NCCCC2C=C1
CAS NO.: 1629249-40-6; 3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride. PROPERTIES: 3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrollidin-1-yl)butanoic acid hydrochloride manifests as a hygroscopic crystalline powder with characteristic acid salt properties. This complex molecule contains multiple chiral centers but is typically supplied as a mixture of stereoisomers. Its molecular formula of C32H38N6O2 HCl results in a molecular weight of approximately 597.19 g/mol. The compound demonstrates pH-dependent solubility, being more soluble in water at basic pH due to protonation of the carboxylic acid group. Thermally stable up to 100 C, decomposition occurs at higher temperatures with potential release of nitrogen-containing fumes. 3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride requires storage between 2-8 degree Celsius in desiccated conditions to prevent moisture-induced degradation. When handling this substance, care should be taken to avoid inhalation of dust and direct skin contact. In case of eye contact, immediate rinsing with water for 15 minutes is advised. The compound's complex structure necessitates careful documentation of material safety data. APPLICATIONS: 3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride represents a multifunctional molecule with potential therapeutic applications. The integration of pyrazole, naphthyridine, and pyrrolidine moieties creates a scaffold suitable for modulating various biological targets. Researchers investigate this compound's utility in kinase inhibition studies, particularly focusing on its interaction with receptor tyrosine kinases. The carboxylic acid group enables covalent binding to target proteins, enhancing residence time. Medicinal chemists exploit the tetrahydronaphthyridine segment to improve CNS penetration while the pyrazole unit contributes to metabolic stability. 3-(3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl)-4-(3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic acid hydrochloride derivatives are evaluated in preclinical models of inflammatory diseases and oncology. Proper cold storage (2-8 C) preserves the integrity of labile amine groups, ensuring consistent biological activity in experimental assays.
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