(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate
$400.00
CAS No.: 955406-14-1
Catalog No.: 192667
Purity: 95%
MF: C12H19N3O2
MW: 237.303
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C[C@@H](CCC12)NC(OC(C)(C)C)=O
Catalog No.: 192667
Purity: 95%
MF: C12H19N3O2
MW: 237.303
Storage: 2-8 degree Celsius
SMILES: N1N=CC=2C[C@@H](CCC12)NC(OC(C)(C)C)=O
(R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate; CAS No.: 955406-14-1; (R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate. PROPERTIES: This chiral carbamate-protected tetrahydroindazole has molecular formula C12H19N3O2. It generally appears as a white crystalline powder. The (R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate exhibits limited water solubility but good solubility in polar aprotic solvents like DMSO and DMF. Its melting point is approximately 108-112 C, and it has a molecular weight of about 237.3 g/mol. When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The compound is sensitive to strong acids and may undergo carbamate hydrolysis upon exposure to aqueous conditions. In case of spillage, absorb with inert material and dispose of in accordance with local regulations. APPLICATIONS: The (R)-tert-butyl 4,5,6,7-tetrahydro-1H-indazol-5-ylcarbamate functions as a valuable intermediate in the synthesis of chiral pharmaceuticals targeting GPCR receptors where the tetrahydroindazole ring provides essential binding interactions with receptor subtypes (as reported in medicinal chemistry literature). The chiral center ensures proper orientation for optimal receptor binding. Additionally, the compound serves as a building block in the preparation of chiral materials for organic electronics with specific charge transport properties, useful in field-effect transistors with mobility values exceeding 0.1 cm?/Vs as described in materials science publications. The carbamate protecting group allows for controlled deprotection under mild acidic conditions.
Reviews
Write Your Own Review