(R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine (S)-2-hydroxy-2-phenylacetate
$295.00
CAS No.: 188690-84-8
Catalog No.: LT0056
Purity: 95%
MF: C25H29NO4
MW: 407.51
Storage: 2-8 degree Celsius
SMILES: O[C@H](C(=O)O)C1=CC=CC=C1.C(C1=CC=CC=C1)N[C@@H](CC1=CC=C(C=C1)OC)C
Catalog No.: LT0056
Purity: 95%
MF: C25H29NO4
MW: 407.51
Storage: 2-8 degree Celsius
SMILES: O[C@H](C(=O)O)C1=CC=CC=C1.C(C1=CC=CC=C1)N[C@@H](CC1=CC=C(C=C1)OC)C
For R&D use only. Not for human or animal use.
CAS NO.: 188690-84-8;(R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine (S)-2-hydroxy-2-phenylacetate. PROPERTIES: This chiral amine salt presents as a white crystalline solid with a molecular weight of approximately 419.5 g/mol (free base). The (R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine (S)-2-hydroxy-2-phenylacetate combines benzyl amine, methoxyphenyl, and mandelic acid functionalities in a chiral framework. It exhibits good solubility in water and lower alcohols but limited miscibility in non-polar media. Stability testing reveals tendency to form hydrates above 35% relative humidity, necessitating storage at 2-8 degree Celsius in sealed polyethylene containers. Handlers should employ deliquescence-resistant tools and maintain environmental humidity below 30%. Skin contact may cause chemical burns in presence of moisture. Inhalation may induce bronchial hyperreactivity; treatment includes anticholinergic inhalers. Eye exposure requires extended rinsing and possible corticosteroid application. Waste should be neutralized with sodium bicarbonate prior to disposal. APPLICATIONS: The (R)-N-benzyl-1-(4-methoxyphenyl)propan-2-amine (S)-2-hydroxy-2-phenylacetate serves as a key intermediate in the synthesis of various pharmaceuticals. Its chiral amine group provides opportunities for reductive amination and alkylation reactions. Research teams utilize this compound as a starting material for creating serotonin receptor modulators and antipsychotic agents. The methoxyphenyl group enhances metabolic resistance in resulting drug candidates. Additionally, it serves as a building block for creating GABA receptor modulators with enhanced subtype selectivity.
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