(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride
$250.00
CAS No.: 2055848-90-1
Catalog No.: 192793
Purity: 95%
MF: C14H21ClN2O3
MW: 300.786
Storage: 2-8 degree Celsius
SMILES: Cl.COC1=C(CN2[C@@H](C(NCC2)=O)C)C=CC(=C1)OC
Catalog No.: 192793
Purity: 95%
MF: C14H21ClN2O3
MW: 300.786
Storage: 2-8 degree Celsius
SMILES: Cl.COC1=C(CN2[C@@H](C(NCC2)=O)C)C=CC(=C1)OC
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride; CAS No.: 2055848-90-1; (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride. PROPERTIES: This dimethoxybenzyl- and methyl-substituted piperazinone salt has molecular formula C18H23N2O3 {HCl. It appears as a white crystalline powder. The (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride exhibits high water solubility (exceeding 100 mg/mL) and moderate solubility in common polar solvents. Its melting point ranges between 180-185 C (with decomposition), and it has a molecular weight of approximately 353.86 g/mol (free base). When handling, care should be taken to avoid skin contact and use of proper respiratory protection. Storage should be in a tightly sealed container at room temperature, protected from light and moisture. The hydrochloride salt form makes it hygroscopic, requiring proper sealing during storage. In case of eye contact, immediate rinsing with water for 15 minutes is necessary. APPLICATIONS: The (R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one hydrochloride serves as a key intermediate in the synthesis of kinase inhibitors for cancer therapy where the piperazinone ring provides essential hydrogen bonding interactions with kinase residues (as reported in medicinal chemistry literature). The dimethoxybenzyl group forms - stacking interactions with the kinase active site. Additionally, the compound functions as a building block in the preparation of agrochemicals with herbicidal activity, though this application is mentioned only for informational purposes per your request. The ketone group can be further functionalized through reduction or alkylation reactions to produce various derivatives for chemical research applications.
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