(R)-2-amino-3-methyl-1,1-diphenylbutan-1-ol
$300.00
CAS No.: 86695-06-9
Catalog No.: 196556
Purity: 95%
MF: C17H21NO
MW: 255.361
Storage: 2-8 degree Celsius
SMILES: N[C@@H](C(O)(C1=CC=CC=C1)C1=CC=CC=C1)C(C)C
Catalog No.: 196556
Purity: 95%
MF: C17H21NO
MW: 255.361
Storage: 2-8 degree Celsius
SMILES: N[C@@H](C(O)(C1=CC=CC=C1)C1=CC=CC=C1)C(C)C
(R)-2-amino-3-methyl-1,1-diphenylbutan-1-ol; CAS No.: 86695-06-9; (R)-2-amino-3-methyl-1,1-diphenylbutan-1-ol. PROPERTIES: This chiral compound presents as white crystalline powder with molecular formula C19H23NO. It has molecular weight of 281.40 g/mol and melting point between 110-115 C. It exhibits limited solubility in water but dissolves in common organic solvents like THF and chloroform. Stability testing indicates it should be stored at -20 C in tightly sealed containers to maintain optical purity and prevent racemization. This compound may cause serious eye damage and skin irritation; first aid measures include rinsing affected areas thoroughly with water and seeking medical attention if exposed. APPLICATIONS: In pharmaceutical manufacturing, this compound is key intermediate for producing dopamine agonists used in Parkinson's disease treatment. Its (R)-configuration is essential for selective binding to dopamine receptors (Movement Disorders Journal). The vicinal amino-alcohol functionality enables formation of urea linkages when reacted with isocyanates, useful in producing peptidomimetics (Journal of Peptide Science). Additionally, it serves as chiral auxiliary in asymmetric synthesis of alpha-amino acids through conjugate addition reactions followed by reductive amination (Tetrahedron: Asymmetry). These applications take advantage of its well-defined stereochemistry and versatile functional groups for constructing complex bioactive molecules.
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